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TRAP 5 ELISA Kit BioAssay(TM) (Tartrate-resistant Acid Phosphatase Serum band 5, TRAcP 5, ACP5, PAP, EC

Cat no: T8266-96

Supplier: United States Biological
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This Human TRAP 5 Assay is an ImmunoCapture Enzyme-Activity Assay for the quantitative measurement of human TRAP 5 in serum and EDTA plasma. It is intended for in vitro diagnostic use only. Species Crossreactivity: canine, monkey and rabbit. TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5; EC is a glycoprotein of 35-37kD. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process. High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased serum levels are observed during normal bone growth among healthy children. Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption such as Paget
Catalogue number: T8266-96
Size: 1Kit
References: 1. Minkin C. Calcif Tissue Int. 1982, 34, 285-290.2. Lau KH, et al Clin Chem. 1987, 33, 458-462.3. Nakanishi M,et al Clin Chem. 1998, 44, 221-225.4. Halleen JM, et al J Bone Miner Res. 2000, 15, 133-1345.5. Lamp EC, et al . Leuk Lymphoma. 2000, 39, 477-484.6. Nakanishi M, et al Clin Chem. 2000, 46, 469-473.7. Waguespack SG et al J Clin Endocrinol Metab. 2002, 87, 2212-2217.8. Igarashi Y, et al . J Chromatogr B. 2002, 781, 345-358.9. Terpos E, et al Int J Cancer. 2003, 106, 455-457.

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