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Microarray Technology

Microarray Technology
Looking for reliable and cost effective Microarray Technology products for your research?

Microarray technology is a method of greatly increasing the throughput of laboratory processes to efficiently perform large-scale genetic tests, such as comparing gene expression between healthy and tumorous tissues. DNA microarray technology is being used for research on heart disease, mental illness and infectious diseases, as well as for developing targeted cancer treatment strategies.

Performing a microarray analysis requires a machine that can automatically dispense tens of thousands of microscopic dots of DNA fragments in a regular matrix, or array, on the surface of a slide. The slide is called a DNA chip and the deposited DNA spots are called probes, or oligos. The probes are covalently bound to the surface of the slide, or synthesized directly on the slide, and a computer keeps track of which probe is located at each position. Alternatively, the probes are bound to microscopic polystyrene beads.

To prepare the target, DNA samples are purified, treated with reverse transcriptase (RT) enzyme to generate complementary DNA (cDNA), and then coupled with fluorescent or chemiluminescent dye molecules, to allow test results to be read. To perform the microarray analysis, the target cDNA is “hybridized” to the DNA probes on the chip with hydrogen bonds that naturally form between complementary nucleic acid sequences on the target and the probes. The more complementarity, the more strongly the target will bind to each specific probe on the chip.

The relative amounts of cDNA that have been bound to each probe can be “read” by a machine scanning the chip with a laser to illuminate the dye molecules, and then processing the image to detect the presence and strength of dye found at each spot.

Equipment and supplies used for microarray technology includes homogenizers, heating and cooling blocks, and mini-centrifuges to prepare the target; DNA, RNA and protein extraction kits; automated nucleic acid purification equipment; PCR systems to amplify the target; and microscopes and spectroscopes to read the  test results.

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TimePro Kinetic Microspectroscopy
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CRAIC Technologies, inc.

Software for CRAIC microspectrometers to measure spectral response over time.Watch video HERE

UVM-1  UV Microscope
UVM-1 UV Microscope
CRAIC Technologies, inc.

Microscope able to image in UV, visible and NIR regionsWatch video HERE

Apollo Raman Microspectrometer
Apollo Raman Microspectrometer
CRAIC Technologies, inc.

Add Raman spectroscopy to your microscopeWatch video HERE

508 PV Microscope Spectrometer
508 PV Microscope Spectrometer
CRAIC Technologies, inc.

Add UV-visible-NIR and Fluorescence spectroscopy to your microscopeWatch Video HERE

20/30 PV Microspectrometer
20/30 PV Microspectrometer
CRAIC Technologies, inc.

UV-visible-NIR reflectance, absorbance, fluorescence and Raman spectra & imaging of microscopic samplesWatch our video HERE

Fluorescent custom oligonucleotides
Fluorescent custom oligonucleotides
IBA GmbH

Excellent service for custom-made fluorescently labeled oligonucleotides. More than 150 labels to choose from Double or multiple labeling possible. Licensed...

Custom oligo synthesis
Custom oligo synthesis
IBA GmbH

Oligos you can rely on - a custom service for specialized, modified nucleic acid products: - DNA oligonucleotides up to 200 bases - RNA, dsRNA (RNAi), random...

Custom RNA duplexes (RNAi)
Custom RNA duplexes (RNAi)
IBA GmbH

High quality custom synthesis of Ready-to-use RNA duplexes (RNAi). Purified, deprotected and annealed. Negative control (corresponding sense and antisense...

Custom Real-time PCR probes
Custom Real-time PCR probes
IBA GmbH

High quality custom synthesis of Real-time PCR probes: a large selection of dye combinations suitable for Real-time PCR is available. 5'- , 3'- or internal...

CellMaxx™ Bovine Albumin, Stem Cell Grade
CellMaxx™ Bovine Albumin, Stem Cell Grade
MP Biomedicals

CellMaxx™ albumin has been used in stem cell culture and to improve protein expression from primary cell lines.Chromatographic purification of...

PlantCon™ presterilized, disposable, plastic growth containers
PlantCon™ presterilized, disposable, plastic growth containers
MP Biomedicals

PlantCon™ from MP Biomedicals is a line of presterilized, disposable, plastic growth containers. This labware was designed to reduce the time spent...

NanoPorter™ NanoTransfection Reagent
NanoPorter™ NanoTransfection Reagent
MP Biomedicals

NanoPorter™ is a new generation transfection reagent for adherent and suspension cells that ensures effective and reproducible transfection with low...

FastPrep® Extraction Kits
FastPrep® Extraction Kits
MP Biomedicals

The FastPrep® portfolio of versatile extraction kits, including the FastDNA™, FastRNA™, and FastProtein™ kits are designed to deliver...

GeneClean® Kits
GeneClean® Kits
MP Biomedicals

The GeneClean® Kits are designed to optimally purify DNA from solutions, agarose gels, acrylamide gels and enzyme reactions. DNA purified with...

Encapsulated Media
Encapsulated Media
MP Biomedicals

MP Biomedicals now offers a wide range of Bacterial and Yeast Media now available in our exclusive encapsulated format. Encapsulated media not only provides...

RapidGene-12™ Automated Nucleic Acid Purification System
RapidGene-12™ Automated Nucleic Acid Purification System
MP Biomedicals

RapidGene-12™ is a compact, automated nucleic acid purification instrument for the extraction and purification of high quality DNA and RNA based on...

FastPrep-24™ High-Speed Benchtop Homogenizer
FastPrep-24™ High-Speed Benchtop Homogenizer
MP Biomedicals

The FastPrep-24™ Instrument is a high-speed benchtop homogenizer offering the ultimate in speed and performance for the lysis of biological samples....

MP Adsorbents for Chromatography
MP Adsorbents for Chromatography
MP Biomedicals

MP Adsorbents for chromatography are highly standardized quality products for all ranges of application in laboratory and industrial scale chromatography. MP...

Mycoplasma Removal Agent (MRA) for mycoplasma contamination in cell cultures
Mycoplasma Removal Agent (MRA) for mycoplasma contamination in cell cultures
MP Biomedicals

Mycoplasma Removal Agent (MRA) from MP offers a highly effective solution for the serious problem of mycoplasma contamination in cell cultures. MRA is a...

BioDrop
BioDrop
BioDrop Ltd

BioDrop, a revolutionary microvolume cuvette, provides a robust, accurate and affordable approach to low volume spectroscopy. BioDrop’s simple but...

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