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Cell Signaling

Cell Signaling
Looking for reliable and cost effective Cell Signaling products for your research?

Living cells communicate information both within the cell itself, and to other cells using a variety of cell signaling pathways. These pathways involve interactions of protein molecules, specifically antibodies and enzymes, created from specific genes in the cell’s DNA.


By studying antibodies and enzymes and their role in cell regulation, signaling and transduction, researchers can determine the molecular pathways leading to specific diseases, and attempt to alter those pathways. For example, by studying the antibody Interleukin 10 (IL-10), researchers have found that defects in IL-10 are a cause of susceptibility to Crohn disease.

Biological researchers use a variety of equipment to study cell signaling pathways, such as microscope-mounted mechanical stretch-strain cell instruments to simulate the bi-axial forces of stretching or compression on growing endothelial, muscle, and fibroblast cells.

Other cell signaling research equipment includes protein analysis tools, such as an instrument that automates all manual operations associated with Western blotting; a multiplex fluorescent detection and chemiluminescent imaging system; magnet assisted transfection (MATra) systems to transfect nucleic acids from plasmid DNA, siRNA or oligonucleotides; and microarray hybridization stations.

Accessories used in cell signaling research include qPCR primers; well tissue culture plates; microplate washers; microplate readers; and biological stirrers designed for optimal suspension cell culture and the use of microcarriers. Commercially available antibodies used in cell signaling research include insulin-like growth factors IGF1 and IGF2, CD3, CD4 (the primary cellular receptor for HIV), CD31, CD 20, CD 34, CD 68, and others.

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MTT Cell Viability and Proliferation Assay Kit
MTT Cell Viability and Proliferation Assay Kit
B-Bridge International, Inc.

Innoprot MTT Cell Viability & Proliferation Assay allows simple, accurate and reliable counting of metabolically active cells, based on the conversion of...

Caspase 3-7 Activity Assay Cell Line
Caspase 3-7 Activity Assay Cell Line
B-Bridge International, Inc.

This MitoCASPred/SH-SY5Y cell line has been developed through stable transfection for monitoring the caspase-3 activity level through the turboFP602 protein...

Green Fluorescent Cytochrome c Mitochondrial Apoptosis Assay Cell Line
Green Fluorescent Cytochrome c Mitochondrial Apoptosis Assay Cell Line
B-Bridge International, Inc.

A novel HEK293/Cytc-tGFP cell line has been developed through stable transfection for monitoring the cellular apoptosis level trhougth the Cytochrome c...

ALS Model: FUS/TLS Stess Granules Assay Cell Line
ALS Model: FUS/TLS Stess Granules Assay Cell Line
B-Bridge International, Inc.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that is characterized by premature degeneration of motor neurons, resulting in a...

PD Model: Parkin Mitochondrial Recrutiment Assay Cell Line
PD Model: Parkin Mitochondrial Recrutiment Assay Cell Line
B-Bridge International, Inc.

Parkinson's disease (PD) is a neurodegenerative disorder caused by the death of dopamine producing cells in the substantia nigra in the brain. The main...

ALS Model:TDP-43 Stress Granules Assay Cell Line
ALS Model:TDP-43 Stress Granules Assay Cell Line
B-Bridge International, Inc.

Amyotrophic lateral sclerosis (ALS) is one of the most common degenerative disease of the motor neuron system.The TDP-43 pathology seems to be a dominant...

Neurite Outgrowth & Mitosis Assay Cell Line
Neurite Outgrowth & Mitosis Assay Cell Line
B-Bridge International, Inc.

A novel green fluorescent SH-SY5Y cell line has been developed through stable transfection with tubulin tagged Evrogen TagGFP2. This cell line expresses...

AD Model: Tau Phosphorylation Assay Cell Line
AD Model: Tau Phosphorylation Assay Cell Line
B-Bridge International, Inc.

The microtubule associated protein Tau is the main component of the neurofribillary tangles (NFT), aberrant structures that appear in the brain of...

APP-C99-tGFP U2OS Stable Cell line: Division-Arrested
APP-C99-tGFP U2OS Stable Cell line: Division-Arrested
B-Bridge International, Inc.

Alzheimer disease (AD) is characterized by brain depositions of the beta amyloid (Beta-A). The Beta-A is the amyloid precursor protein (APP) digestion...

AD Model: Gamma-Secretase Activity Assay Cell Line
AD Model: Gamma-Secretase Activity Assay Cell Line
B-Bridge International, Inc.

Alzheimer disease (AD) is characterized by brain depositions of the beta amyloid (Beta-A). The Beta-A is the amyloid precursor protein (APP) digestion...

Gamma & Beta Secretase Activity Assay Cell Line Division Arrested
Gamma & Beta Secretase Activity Assay Cell Line Division Arrested
B-Bridge International, Inc.

Gamma & Beta Secretase Activity Assay Cell Line Division Arrested

AD Model: Amyloid Precursor Protein (APP) Secretase Activity Assay Cell Line
AD Model: Amyloid Precursor Protein (APP) Secretase Activity Assay Cell Line
B-Bridge International, Inc.

AlzheimerA^'s Disease (AD) is characterized by brain depositions of the beta amyloid (bA). The bA is the amyloid precursor protein (APP) digestion product,...

AD Model: Beta-Secretase Expression Assay tGFP-BACE1 HEK293 Cell Line
AD Model: Beta-Secretase Expression Assay tGFP-BACE1 HEK293 Cell Line
B-Bridge International, Inc.

A novel HEK293/tGFP-BACE cell line has been developed through stable transfection for monitoring the expression of beta-secretase in cell-based assays....

Nuclear Apoptosis Assay Cell Line
Nuclear Apoptosis Assay Cell Line
B-Bridge International, Inc.

A SH-SY5Y/TagRFP-LaminB1 cell line and a U2OS/TagRFP-LaminB1 cell lines has been developed through stable transfection for monitoring the cellular apoptosis...

Melanocortin 4 Receptor stable expressing HEK293 cell line
Melanocortin 4 Receptor stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker MC4R Cell Line has been designed to assay compounds or analyze their capability to modulate human Melanocortin 4 Receptor. When an agonist...

Prostaglandin E Receptor 2 - subtype EP2 stable expressing HEK293 cell line
Prostaglandin E Receptor 2 - subtype EP2 stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker PTGER2 Cell Line has been designed to assay compounds or analyze their capability to modulate human Prostaglandin E Receptor 2 - subtype...

Prostaglandin E Receptor 1 - subtype EP1 stable expressing HEK293 cell line
Prostaglandin E Receptor 1 - subtype EP1 stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker PTGER1 Cell Line has been designed to assay compounds or analyze their capability to modulate human Prostaglandin E Receptor 1 - subtype...

Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
B-Bridge International, Inc.

Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested

Fluorescent Androgen Receptor Nuclear Translocation Assay
Fluorescent Androgen Receptor Nuclear Translocation Assay
B-Bridge International, Inc.

tGFP-hAR/HEK293 contains HEK293 cells stably expressing human Androgen Receptor (AR) tagged with tGFP. Innoprot's AR Nuclear Translocation Assay kit has been...

Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
B-Bridge International, Inc.

Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested

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