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Drug Discovery

Drug Discovery
Looking for reliable and cost effective Drug Discovery products for your research?

The drug discovery and development process has traditionally taken 12 to 15 years to identify a potential target and molecule in the lab; synthesize and screen the molecule; test the molecule in vitro and in humans; perform clinical trials; obtain regulatory approval (Pharmacopeia, GLP and/or ISO); develop and scale-up manufacturing processes; and begin commercial production and shipping.

Because of the extended time to market and expense of developing new drugs, the pharmaceutical business is focusing on more disruptive discoveries, such as curing an incurable disease or preventing a disease, rather than just developing new drugs that produce only slight improvements. New paradigms in drug discovery are evolving to reduce development time and expense by networking multi-functional teams which are patient-focused.

Laboratory instruments for drug discovery include protein interaction array systems; gamma counters; HPLC systems; microplate luminometers and fluorometers; mass spectrometers; microarray scanners; hybridization reaction stations; and modular plant imaging systems.

Equipment, consumables and services for drug discovery labs include transfection reagents; cDNA and RNA synthesis kits; assay and ELISA kits; melting point apparatuses; microplate washers; cryogenic freezers; cryogenic tubes; ergonomic and multichannel pipettes and pipette tip racks and refills; pluripotent stem cells; reaction plates and modules; tumor tissue with matched blood samples; custom protein production in E. coli; injection services; DNA sequencing services; tissue homogenizers; and biobanking software.

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MTT Cell Viability and Proliferation Assay Kit
MTT Cell Viability and Proliferation Assay Kit
B-Bridge International, Inc.

Innoprot MTT Cell Viability & Proliferation Assay allows simple, accurate and reliable counting of metabolically active cells, based on the conversion of...

Caspase 3-7 Activity Assay Cell Line
Caspase 3-7 Activity Assay Cell Line
B-Bridge International, Inc.

This MitoCASPred/SH-SY5Y cell line has been developed through stable transfection for monitoring the caspase-3 activity level through the turboFP602 protein...

Green Fluorescent Cytochrome c Mitochondrial Apoptosis Assay Cell Line
Green Fluorescent Cytochrome c Mitochondrial Apoptosis Assay Cell Line
B-Bridge International, Inc.

A novel HEK293/Cytc-tGFP cell line has been developed through stable transfection for monitoring the cellular apoptosis level trhougth the Cytochrome c...

ALS Model: FUS/TLS Stess Granules Assay Cell Line
ALS Model: FUS/TLS Stess Granules Assay Cell Line
B-Bridge International, Inc.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that is characterized by premature degeneration of motor neurons, resulting in a...

PD Model: Parkin Mitochondrial Recrutiment Assay Cell Line
PD Model: Parkin Mitochondrial Recrutiment Assay Cell Line
B-Bridge International, Inc.

Parkinson's disease (PD) is a neurodegenerative disorder caused by the death of dopamine producing cells in the substantia nigra in the brain. The main...

ALS Model:TDP-43 Stress Granules Assay Cell Line
ALS Model:TDP-43 Stress Granules Assay Cell Line
B-Bridge International, Inc.

Amyotrophic lateral sclerosis (ALS) is one of the most common degenerative disease of the motor neuron system.The TDP-43 pathology seems to be a dominant...

Neurite Outgrowth & Mitosis Assay Cell Line
Neurite Outgrowth & Mitosis Assay Cell Line
B-Bridge International, Inc.

A novel green fluorescent SH-SY5Y cell line has been developed through stable transfection with tubulin tagged Evrogen TagGFP2. This cell line expresses...

AD Model: Tau Phosphorylation Assay Cell Line
AD Model: Tau Phosphorylation Assay Cell Line
B-Bridge International, Inc.

The microtubule associated protein Tau is the main component of the neurofribillary tangles (NFT), aberrant structures that appear in the brain of...

APP-C99-tGFP U2OS Stable Cell line: Division-Arrested
APP-C99-tGFP U2OS Stable Cell line: Division-Arrested
B-Bridge International, Inc.

Alzheimer disease (AD) is characterized by brain depositions of the beta amyloid (Beta-A). The Beta-A is the amyloid precursor protein (APP) digestion...

AD Model: Gamma-Secretase Activity Assay Cell Line
AD Model: Gamma-Secretase Activity Assay Cell Line
B-Bridge International, Inc.

Alzheimer disease (AD) is characterized by brain depositions of the beta amyloid (Beta-A). The Beta-A is the amyloid precursor protein (APP) digestion...

Gamma & Beta Secretase Activity Assay Cell Line Division Arrested
Gamma & Beta Secretase Activity Assay Cell Line Division Arrested
B-Bridge International, Inc.

Gamma & Beta Secretase Activity Assay Cell Line Division Arrested

AD Model: Amyloid Precursor Protein (APP) Secretase Activity Assay Cell Line
AD Model: Amyloid Precursor Protein (APP) Secretase Activity Assay Cell Line
B-Bridge International, Inc.

AlzheimerA^'s Disease (AD) is characterized by brain depositions of the beta amyloid (bA). The bA is the amyloid precursor protein (APP) digestion product,...

AD Model: Beta-Secretase Expression Assay tGFP-BACE1 HEK293 Cell Line
AD Model: Beta-Secretase Expression Assay tGFP-BACE1 HEK293 Cell Line
B-Bridge International, Inc.

A novel HEK293/tGFP-BACE cell line has been developed through stable transfection for monitoring the expression of beta-secretase in cell-based assays....

Nuclear Apoptosis Assay Cell Line
Nuclear Apoptosis Assay Cell Line
B-Bridge International, Inc.

A SH-SY5Y/TagRFP-LaminB1 cell line and a U2OS/TagRFP-LaminB1 cell lines has been developed through stable transfection for monitoring the cellular apoptosis...

Melanocortin 4 Receptor stable expressing HEK293 cell line
Melanocortin 4 Receptor stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker MC4R Cell Line has been designed to assay compounds or analyze their capability to modulate human Melanocortin 4 Receptor. When an agonist...

Prostaglandin E Receptor 2 - subtype EP2 stable expressing HEK293 cell line
Prostaglandin E Receptor 2 - subtype EP2 stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker PTGER2 Cell Line has been designed to assay compounds or analyze their capability to modulate human Prostaglandin E Receptor 2 - subtype...

Prostaglandin E Receptor 1 - subtype EP1 stable expressing HEK293 cell line
Prostaglandin E Receptor 1 - subtype EP1 stable expressing HEK293 cell line
B-Bridge International, Inc.

Innoprot HiTSeeker PTGER1 Cell Line has been designed to assay compounds or analyze their capability to modulate human Prostaglandin E Receptor 1 - subtype...

Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
B-Bridge International, Inc.

Fluorescent Androgen Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested

Fluorescent Androgen Receptor Nuclear Translocation Assay
Fluorescent Androgen Receptor Nuclear Translocation Assay
B-Bridge International, Inc.

tGFP-hAR/HEK293 contains HEK293 cells stably expressing human Androgen Receptor (AR) tagged with tGFP. Innoprot's AR Nuclear Translocation Assay kit has been...

Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested
B-Bridge International, Inc.

Fluorescent Glucocorticoid Receptor Nuclear Translocation Assay HEK293 Cells Division Arrested

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