Home  >  Products  >  Syntrophin (Syntrophin 1, Syntrophin-1, Syntrophin alpha 1, SNTA1, 59kD Dystrophin-associated Protein A1 Acidic Component 1, Dystrophin-associated Protein A1 59kDa Acidic Component, Dystrophin-associated Protein A1, Pro-TGF-alpha Cytoplasmic Domain-intera
Syntrophin (Syntrophin 1, Syntrophin-1, Syntrophin alpha 1, SNTA1, 59kD Dystrophin-associated Protein A1 Acidic Component 1, Dystrophin-associated Protein A1 59kDa Acidic Component, Dystrophin-associated Protein A1, Pro-TGF-alpha Cytoplasmic Domain-intera

Syntrophin (Syntrophin 1, Syntrophin-1, Syntrophin alpha 1, SNTA1, 59kD Dystrophin-associated Protein A1 Acidic Component 1, Dystrophin-associated Protein A1 59kDa Acidic Component, Dystrophin-associated Protein A1, Pro-TGF-alpha Cytoplasmic Domain-intera

Cat no: S9299-95C

Supplier: United States Biological
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Syntrophin (alpha-1) is a peripheral membrane protein located at the neuromuscular junction. Syntrophin (alpha-1) is expressed at high levels in skeletal muscle and heart, and at lower levels in brain, pancreas, liver, kidney and lung. It is an adaptor protein which is thought to bind and organise the subcellular localisation of membrane proteins such as utrophin and acetylcholine receptor. Syntrophin (alpha-1) also binds phosphatidylinositol 4,5-bisphosphate, it may link various receptors to the dystrophin glycoprotein complex and the actin cytoskeleton. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.5ug/ml detects a band of ~60kD in human brain cell lysates. A minimum incubation time of 1 hour is recommended with this antibody. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S9299-95C
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Ahn, A. et al. (1996) The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives. J. Biol. Chem. 271: 2724-2730.
Additional info: Recognizes human Syntrophin alpha 1. Species sequence homology: mouse, rat.

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