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SYN1 (Synapsin-1, Brain Protein 4.1, Synapsin I)

Cat no: S9104-04F

Supplier: United States Biological
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Synapsins are involved in neurotransmitter release. Synapsin I cross-links synaptic vesicles and cytoskeleton. The interactions of the protein with actin filaments and synaptic vesicle are regulated by phosphorylation. Synapsin I has many potential phosphorylation sites available to different enzymes, serines 62 and 67 are phosphorylated by extracellular signal-regulated kinases 1 and 2 of the mitogen-activated protein (MAP) kinase superfamily. Map-kinase phosphorylation of synapsins is a key step in the modulation of neurotransmitter release by brain-derived neurotrophic factor. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S9104-04F
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS without Mg2+, Ca2+, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human SYN1. Species sequence homology: Mouse, rat.

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