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SYK, phosphorylated (Y525/Y526) (Spleen Tyrosine Kinase, HGNC:11491, p72Syk, Tyrosine Protein Kinase SYK)

SYK, phosphorylated (Y525/Y526) (Spleen Tyrosine Kinase, HGNC:11491, p72Syk, Tyrosine Protein Kinase SYK)

Cat no: S9100-01X

Supplier: United States Biological
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Spleen tyrosine kinase (SYK) is a 70-80kD, ubiquitously expressed member of the protein kinase superfamily, the tyrosine protein kinase family, and the SYK/ZAP70 subfamily of proteins. Human SYK is 635aa in length and contains two SH2 domains (aa14106 and aa168259 and one protein kinase domain (aa371-631). A splicing variant produces a second isoform that has a deletion of aa371-631 found in the longer isoform. Human SYK shares 92% and 91% aa sequence identity with mouse and rat SYK, respectively. Functionally, SYK is a positive effector of Bcell antigen receptorstimulated responses. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml detects human SYK phosphorylated at Y525/Y526 in Ramos human Burkitt
Catalogue number: S9100-01X
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human SYK when phosphorylated at Y525/Y526.

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