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STYK1 (Tyrosine-protein Kinase STYK1, Serine/Threonine/Tyrosine Kinase 1, Novel Oncogene with Kinase Domain, Protein PK-unique, NOK)

Cat no: S7985-10A


Supplier: United States Biological
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STYK1, a probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. It is widely expressed; highly expressed in brain, placenta and prostate. STYK1 is expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:10,000 Western Blot: 1:500-1:2000 Immunohistochemistry (Formalin fixed paraffin embedded): 1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7985-10A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ul
Form: Supplied as a liquid.
P type: Mab
Isotype: IgG1
Purity: Ascites
Additional info: Recognizes human STYK1.

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