Home  >  Products  >  Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1) (Agarose)

Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1) (Agarose)

Cat no: S7982-03E


Supplier: United States Biological
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Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosome movement. Applications: Suitable for use in Immunoprecipitation. Other applications not tested. Recommended Dilutions: Immunoprecipitation: 15-25ul gel/0.1-1mg protein lysate Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7982-03E
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation
Conjugates: Agarose
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Conjugated to agarose.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human SMC3. Species sequence homology: mouse and bovine

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