STEAP3 is transcriptionally activated by p53, while its gene product associates with Myt1 kinase, a negative regulator of the G2/M transition and with Nix, a proapoptotic Bcl-2 related protein. Elevation of TSAP6 augments cell-cycle delay and apoptosis suggesting that TSAP6 may play a role in tumor suppression.
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Western Blot: 1-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.