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STAT 4 (Signal Transducer and Activator of Transcription 4)

Cat no: S7972-02J

Supplier: United States Biological
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STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. Stat 4 is activated when cells are treated with interleukin-12, a key cytokine regulator of cell-mediated immunity. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Mouse or rat testes Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7972-02J
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 200ul
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Holly A., et al. J. Biol. Chem. 273:17109-17114 (1998) 2. David Farrar, et al. J. Biol. Chem. 275:2693-2697 (2000) 3. Nakahira M, et al. J Immunol.168(3):1146-1153(2002) 4. Kato A, et al. Transplantation 73(7):1142-1145(2002) 5. Battle TE, et al. Curr Mol Med 2(4):381-92(2002).
Additional info: Recognizes mouse STAT4. Species Crossreactivity: rat. Species sequence homology: human.

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