Home  >  Products  >  STAP2 (Signal Transducing Adaptor Family Member 2, Signal Transducing Adaptor Protein 2, STAP-2, Breast Tumor Kinase Substrate, BRK Substrate, BKS, FLJ20234)
STAP2 (Signal Transducing Adaptor Family Member 2, Signal Transducing Adaptor Protein 2, STAP-2, Breast Tumor Kinase Substrate, BRK Substrate, BKS, FLJ20234)

STAP2 (Signal Transducing Adaptor Family Member 2, Signal Transducing Adaptor Protein 2, STAP-2, Breast Tumor Kinase Substrate, BRK Substrate, BKS, FLJ20234)

Cat no: S7954-65

Supplier: United States Biological
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This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S7954-65
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Minoguchi M, Minoguchi S, Aki D, Joo A, Yamamoto T, Yumioka T, Matsuda T, Yoshimura A. STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif. J Biol Chem. 2003 Mar 28;278(13):11182-9. Epub 2003 Jan 22. PMID: 12540842
Additional info: Species Crossreactivity: Tested: Human, Expected from sequence similarity: Human

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