EDG6, a Lysophospholipid/Lysosphingolipid Receptor, may regulate lymphocyte cell signaling. EDG6 is activated by sphingosine-1-phosphate. EDG6 has been reported in fetal and adult lymphoid and hematopoietic tissues (Graler et al, 1998) as well as in rat lung and Burkitt lymphoma cell lines. Contrary to other receptors of the EDG family, EDG6 is not expressed in the nervous system.
Suitable for use in Immunohistochemistry. Other applications not tested.
Immunohistochemistry (paraffin): 8-19ug/ml
Optimal dilutions to be determined by the researcher.
Human Lymph node
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.