Home  >  Products  >  Speedy-1 (SPDY1, SPY1, Speedy Homolog A, SPDYA, MGC110856, MGC57218, Rapid Inducer of G2/M Progression in Oocytes A, Ringo3)

Speedy-1 (SPDY1, SPY1, Speedy Homolog A, SPDYA, MGC110856, MGC57218, Rapid Inducer of G2/M Progression in Oocytes A, Ringo3)

Cat no: S5383


Supplier: United States Biological
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Speedy/Ringo (Spy1) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. It mediates cell survival during the DNA damage process through activation of CDK2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Mouse testis lysate Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S5383
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Tris-citrate/phosphate (pH 7-8)
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Porter, LA., Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. JCB. 157(3): 357-366 (2002)
Additional info: This antibody is specific for human Speedy/Ringo protein. Species Crossreactivity: Mouse. Other species have not been tested.

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