Home  >  Products  >  Spectrin, beta, Erythrocytic (Erythroid beta-Spectrin, Spectrin beta Chain Erythrocyte, SPTB, Beta-I Spectrin, SPTB1, EL3, HS2, HSPTB1, SPH2)
Spectrin, beta, Erythrocytic (Erythroid beta-Spectrin, Spectrin beta Chain Erythrocyte, SPTB, Beta-I Spectrin, SPTB1, EL3, HS2, HSPTB1, SPH2)

Spectrin, beta, Erythrocytic (Erythroid beta-Spectrin, Spectrin beta Chain Erythrocyte, SPTB, Beta-I Spectrin, SPTB1, EL3, HS2, HSPTB1, SPH2)

Cat no: S5381-25

Supplier: United States Biological
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Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S5381-25
Reactivities: Human
Hosts: Mouse
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.1 % sodium azide, 1% BSA.
P type: Mab
Isotype: IgG1
Purity: Ascites
Alternative names: Erythroid beta-Spectrin
References: 1. Auranen M. et al. (2000) Neuromusc. Disord. 10, 16-23. 2. Tani T. et al. (1996) Exp. Hematol. 24: 24, 158-168.
Additional info: Recognizes the 220kD human erythroid b-spectrin. Present in the membranes of human skeletal muscle cells.

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