Home  >  Products  >  Spectrin, alpha, Erythrocytic 1 (Erythroid alpha-Spectrin, Spectrin alpha Chain Erythrocyte, SPTA, SPTA1, Elliptocytosis 2, EL2, HPP, HS3, SPH3)

Spectrin, alpha, Erythrocytic 1 (Erythroid alpha-Spectrin, Spectrin alpha Chain Erythrocyte, SPTA, SPTA1, Elliptocytosis 2, EL2, HPP, HS3, SPH3)

Cat no: S5379-98


Supplier: United States Biological
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Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S5379-98
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 1% BSA, 0.1 % sodium azide.
P type: Mab
Isotype: IgG1
Purity: Ascites
References: 1. Tani T. et al. (1996) Exp. Hematol. 24: 24, 158-168.
Additional info: Recognizes the 240kD human erythroid a-spectrin.

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