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SOX4 (Transcription Factor SOX-4)

SOX4 (Transcription Factor SOX-4)

Cat no: S5364-21F

Supplier: United States Biological
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SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S5364-21F
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum.
References: 1. Farr,C.J., Easty,D.J., Ragoussis,J., Collignon,J., Lovell-Badge,R. and Goodfellow,P.N., Characterization and mapping of the human SOX4 gene, Mamm. Genome 4 (10), 577-584 (1993).
Additional info: Recognizes human SOX4. Species sequence homology: bovine, chicken, mouse, rat, xenopus.

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