Home  >  Products  >  Sox 6 (SOX6, SOX-6, SRY Sex Determining Region Y Box 6, SRY (Sex Determining Region Y)-box 6, HSSOX 6, HSSOX6, SRY-box 6, SRY Box Containing Gene 6, Transcription Factor SOX6, Transcription Factor SOX-6)
Sox 6 (SOX6, SOX-6, SRY Sex Determining Region Y Box 6, SRY (Sex Determining Region Y)-box 6, HSSOX 6, HSSOX6, SRY-box 6, SRY Box Containing Gene 6, Transcription Factor SOX6, Transcription Factor SOX-6)

Sox 6 (SOX6, SOX-6, SRY Sex Determining Region Y Box 6, SRY (Sex Determining Region Y)-box 6, HSSOX 6, HSSOX6, SRY-box 6, SRY Box Containing Gene 6, Transcription Factor SOX6, Transcription Factor SOX-6)

Cat no: S5364-23D

Supplier: United States Biological
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The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. SOX6 is a transcriptional factor that is specifically expressed in the developing central nervous system and in the early stages of chondrogenesis in mouse embryos. Results indicate that the developmentally regulated transcription factor SOX6 is aberrantly expressed in glioma. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S5364-23D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: 50% Ammonium sulfate, PBS
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Iguchi H et al. SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. J Biol Chem 280:37669-80 (2005). PubMed: 16148004
Additional info: Species Crossreactivity: This antibody is reactive against human, mouse, rat and primate.

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