Somatostatin was originally isolated from the hypothalamus and characterized by its ability to inhibit release of growth hormone from the pituitary gland. It exists in two forms, somatostatin-14, composed of 14aa and somatostatin-28, a prohormone composed of 28 residues. The Somatostatin antibody will label D cells of the endocrine mammalian pancreas and also cells of the hypothalamic parvicellular region. It may prove useful for the identification of tumors and hyperplasias of the pancreatic islets.
Applications:
Suitable for use in RIA, ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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