Somatostatin was originally isolated from the hypothalamus and characterized by its ability to inhibit release of growth hormone from the pituitary gland. It exists in two forms, somatostatin-14, composed of 14aa and somatostatin-28, a prohormone composed of 28 residues. The Somatostatin antibody will label D cells of the endocrine mammalian pancreas and also cells of the hypothalamic parvicellular region. It may prove useful for the identification of tumors and hyperplasias of the pancreatic islets.
Suitable for use in RIA, ELISA and Immunohistochemistry. Other applications not tested.
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.