SODD, CT (BAG Family Molecular Chaperone Regulator 4, BAG-4, Bcl-2-associated Athanogene 4, Silencer of Death Domains, BAG4)

Cat no: S2000-06B

Supplier: United States Biological

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SODD (Silencer of Death Domain) is an important regulator of TNF induced apoptotic pathway. It associates with TNF-R1 to prevent constitutive activation of the signaling events downstream. It dissociates from the TNF-R1 after TNF binds TNF-R1 to allow the activation of apoptotic pathway. It is expressed ubiquitously in human tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2.5-5ug/ml for 2h at room temperature Optimal dilutions to be determined by the researcher. Positive Control: HeLa cells Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S2000-06B
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	50ug
Form:	Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
P type:	Pab
Purity:	Purified by Protein A affinity chromatography.
Additional info:	Recognizes human SODD.

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SODD, CT (BAG Family Molecular Chaperone Regulator 4, BAG-4, Bcl-2-associated Athanogene 4, Silencer of Death Domains, BAG4)

Cat no: S2000-06B

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