Home  >  Products  >  SOCS 3 (Suppressor of Cytokine Signalling 3, SOCS3, SOCS-3, ATOD4, Cytokine-inducible SH2 Protein 3, CIS3, CIS-3, Cish3, MGC71791, STAT-induced STAT Inhibitor 3, SSI3, SSI-3)
SOCS 3 (Suppressor of Cytokine Signalling 3, SOCS3, SOCS-3, ATOD4, Cytokine-inducible SH2 Protein 3, CIS3, CIS-3, Cish3, MGC71791, STAT-induced STAT Inhibitor 3, SSI3, SSI-3)

SOCS 3 (Suppressor of Cytokine Signalling 3, SOCS3, SOCS-3, ATOD4, Cytokine-inducible SH2 Protein 3, CIS3, CIS-3, Cish3, MGC71791, STAT-induced STAT Inhibitor 3, SSI3, SSI-3)

Cat no: S1040-03B

Supplier: United States Biological
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Members of the SOCS family have been identified due to their marked homology on the SH2 domain and a unique conserved motif referred to as the SOCS box. Expression of SOCS3 is transiently induced in a variety of immune and inflammatory situations by a wide variety of cytokines. SOCS3 is also involved in growth hormone function, leptin and insulin signaling. SOCS3 inhibits Janus kinase (JAK) tyrosine kinase activity. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1040-03B
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 15mM sodium azide, pH7.4.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein A affinity chromatography.
Alternative names: E2a Pbx1 Target Gene in Fibroblasts 10, EF-10
Additional info: Recognizes the cytokine signaling is known to be regulated by a negative feedback regulator called suppressor of cytokine signaling (SOCS) inhibitors family.

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