Home  >  Products  >  SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)
SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)

SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)

Cat no: S1014-97A6

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:64,000 Western Blot: 1-3ug/ml ~75kD band observed in Human lysates of cell line HeLa (calculated MW of 59.1kD according to NP_003090.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1014-97A6
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: HsT17379, MGC8664, SNX1A, Sorting nexin-1, Vps5
References: 1. Mari M, Bujny MV, Zeuschner D, Geerts WJ, Griffith J, Petersen CM, Cullen PJ, Klumperman J, Geuze HJ, SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic (Copenhagen, Denmark) 2008 Mar 9 (3): 380-93
Additional info: Recognizes human SNX1. Species sequence homology: mouse, rat, canine, bovine. This antibody is expected to recognize isoform a and c (NP_003090.2; NP_690039.1).

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave