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SMT3 (Small Ubiquitin-related Modifier 3, SUMO-3, SMT3 Homolog 1, SUMO-2, Ubiquitin-like Protein SMT3A, SMT3A, SMT3H1)

SMT3 (Small Ubiquitin-related Modifier 3, SUMO-3, SMT3 Homolog 1, SUMO-2, Ubiquitin-like Protein SMT3A, SMT3A, SMT3H1)

Cat no: S8026-20G

Supplier: United States Biological
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SMT3 is a Ubiquitin-like protein found in Saccharomyces cerevisiae similar to the mammalian Ubiquitin-like protein SUMO-1, which is involved in posttranslational protein modification. SMT3 is functionally active in regulation of nucleocytoplasmic transport and suggest a role in cell-cycle regulation. Knockdown of SMT3 in Drosophila in the prothoracic gland, which controls key developmental processes through the synthesis and release of ecdysteroids, caused a 4-fold prolongation of larval life and completely blocked the transition from larval to pupal stages. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2-4ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Testis Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S8026-20G
Reactivities: Human, Mouse, Non-Human Primate
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
References: 1. Talamillo, A. et al. Development 135: 1659-1668 (2008). 2. Johnson, E.S. et al. Embo. J. 16: 5509-5519 (1997). 3. Wanyun, S. et al. Protein Sci. 11: 1482-1491 (2002).
Additional info: Recognizes human SMT3. Species Crossreactivity: chimpanzee, equine, monkey, mouse. Species sequence homology: opossum, pufferfish.

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