Home  >  Products  >  SMC2 (Structural Maintenance of Chromosomes Protein 2, SMC Protein 2, SMC-2, Chromosome-associated Protein E, hCAP-E, XCAP-E Homolog, CAPE, SMC2L1, PRO0324)

SMC2 (Structural Maintenance of Chromosomes Protein 2, SMC Protein 2, SMC-2, Chromosome-associated Protein E, hCAP-E, XCAP-E Homolog, CAPE, SMC2L1, PRO0324)

Cat no: S7981-01L


Supplier: United States Biological
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SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7981-01L
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum.
References: 1. Schmiesing,J.A., Ball,A.R. Jr., Gregson,H.C., Alderton,J.M., Zhou,S. and Yokomori,K. Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics Proc. Natl. Acad. Sci. U.S.A. 95 (22), 12906-12911 (1998).
Additional info: Recognizes human SMC2. Species sequence homology: bovine, canine, mouse, rat.

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