Home  >  Products  >  SMAD1 (Mothers Against Decapentaplegic Homolog 1, MAD Homolog 1, Mothers Against DPP Homolog 1, JV4-1, Mad-related Protein 1, SMAD Family Member 1, SMAD 1, hSMAD1, Transforming Growth Factor-beta-signaling Protein 1, BSP-1, BSP1, MADH1, MADR1)
SMAD1 (Mothers Against Decapentaplegic Homolog 1, MAD Homolog 1, Mothers Against DPP Homolog 1, JV4-1, Mad-related Protein 1, SMAD Family Member 1, SMAD 1, hSMAD1, Transforming Growth Factor-beta-signaling Protein 1, BSP-1, BSP1, MADH1, MADR1)

SMAD1 (Mothers Against Decapentaplegic Homolog 1, MAD Homolog 1, Mothers Against DPP Homolog 1, JV4-1, Mad-related Protein 1, SMAD Family Member 1, SMAD 1, hSMAD1, Transforming Growth Factor-beta-signaling Protein 1, BSP-1, BSP1, MADH1, MADR1)

Cat no: S1014-51C

Supplier: United States Biological
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Smad proteins have been implicated as downstream effectors of TGF beta/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF beta and activin mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF beta signaling by interfering with TGF beta mediated phosphorylation of other Smad family members. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot:1:500-1:1,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1014-51C
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Smad1. Species Cross-Reactivity: mouse, rat.

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