SLITRK5 is a member of Slitrk family, a family of neuronal transmembrane proteins that control neurite outgrowth. Structurally, Slitrk family members are characterized by two leucine-rich repeat (LRR) domains located amino-terminally to the transmembrane domain and carboxy-terminally located tyrosine residues which are flanked by aa sequences. SLITRK5 is predominantly expressed in the brain (cerebral cortex). It's gene is localized on human chromosome 13q31.1. The protein plays an important role in suppressing neurite growth. The pathological role of the protein has been identified in various brain tumors.
Suitable for use in ELISA. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.