Home  >  Products  >  SLIRP (SRA Stem-loop-interacting RNA-binding Protein Mitochondrial, Chromosome 14 Open Reading Frame 156, C14orf156, DC50, PD04872)
SLIRP (SRA Stem-loop-interacting RNA-binding Protein Mitochondrial, Chromosome 14 Open Reading Frame 156, C14orf156, DC50, PD04872)

SLIRP (SRA Stem-loop-interacting RNA-binding Protein Mitochondrial, Chromosome 14 Open Reading Frame 156, C14orf156, DC50, PD04872)

Cat no: S1014-18P

Supplier: United States Biological
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SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down estrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml. Band at ~12kD corresponding to SLIRP. May see additional bands above 45kD. Optimal dilutions to be determined by the researcher. Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S1014-18P
Reactivities: Human, Non-Human Primate
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-glycine, 150mM sodium chloride, 0.05% sodium azide
P type: Pab
Purity: Purified by peptide immunoaffinity chromatography.
References: 1. Hatchell, EC, et al. Mol. Cell. 22: 657-668 (2006)
Additional info: Recognizes human and monkey SLIRP protein. Does not cross-react with mouse.

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