Solute carrier family 22 member 2 is a 65kD member of the major facilitator superfamily and organic cation transporter family of proteins. Human SLC22A2 is synthesized as a multipass transmembrane protein that is 555aa in length. Human SLC22A2 contains one potential site for N- linked glycosylation. There are also two additional isoforms for human SLC22A2. Isoform 2 has a 57aa substitution for aa27-483 and a deletion of the 72aa at positions 484-555. Isoform 3 has an 18aa substitution for aa225-242 and a deletion of residues 243-555. SLC22A2 has its highest expression in the kidney. It is also expressed at lower levels in neurons of the cerebral cortex and in various subcortical nuclei.
Suitable for use in Immunohistochemistry. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.