Solute carrier family 22 member 2 is a 65kD member of the major facilitator superfamily and organic cation transporter family of proteins. Human SLC22A2 is synthesized as a multipass transmembrane protein that is 555aa in length. Human SLC22A2 contains one potential site for N- linked glycosylation. There are also two additional isoforms for human SLC22A2. Isoform 2 has a 57aa substitution for aa27-483 and a deletion of the 72aa at positions 484-555. Isoform 3 has an 18aa substitution for aa225-242 and a deletion of residues 243-555. SLC22A2 has its highest expression in the kidney. It is also expressed at lower levels in neurons of the cerebral cortex and in various subcortical nuclei.
Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 8-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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