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SIRT3 (NAD-dependent Protein Deacetylase Sirtuin-3, Mitochondrial, hSIRT3, Regulatory Protein SIR2 Homolog 3, SIR2-like Protein 3, SIR2L3)

SIRT3 (NAD-dependent Protein Deacetylase Sirtuin-3, Mitochondrial, hSIRT3, Regulatory Protein SIR2 Homolog 3, SIR2-like Protein 3, SIR2L3)

Cat no: S1013-88F8

Supplier: United States Biological
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Silent information regulator (Sir2)-like family deacetylases (also known as sirtuins) are highly conserved proteins and have important roles in the regulation of metabolism, inflammation, cellular survival growth and differentiation. SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Yeast sirtuin proteins are found to regulate epigenetic gene silencing. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1013-88F8
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human SIRT3.

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