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Sex Determining Region Y (SRY, Testis Determining Factor, TDF, Testis Determining Factor on Y, TDY)

Sex Determining Region Y (SRY, Testis Determining Factor, TDF, Testis Determining Factor on Y, TDY)

Cat no: S1012-40

Supplier: United States Biological
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Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000-1:5000 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S1012-40
Reactivities: Mouse
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
P type: Mab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Sim H, et al. Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal. Mol. Endocrinol. Jul 2005; 19(7): 1884-1892. 2. Hossain A, Saunders GF. The human sex-determining gene SRY is a direct target of WT1. J. Biol. Chem. May 2001; 276(20): 16817-16823. 3. Yu X, Weissman SM. Characterization of the promoter of human leukocyte-specific transcript 1. A small gene with a complex pattern of alternative transcripts. J. Biol. Chem. Nov 2000; 275(44): 34597-34608.
Additional info: Recognizes mouse SRY protein.

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