Rat Aortic Smooth Muscle Cells (RASMC) provided by Innoprot are isolated from Sprague Dawley rat aorta. RASMC are cryopreserved at secondary culture after purification and delivered frozen. Smooth muscle cell (SMC) is the cellular substate of most significant arterial disease. The increased growth potential of vascular SMC represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate that SMC express calcium channels and the expression of ICAM-1 and VCAM-1 on SMC may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular disease. In vitro culture of rat vascular SMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.
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