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Purified anti-p63 (deltaN)

Purified anti-p63 (deltaN)

Cat no: 619002


Supplier: BioLegend
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p63 (deltaN) is a member of the p53 family. This protein has multiple isoforms TA p63-alpha, -beta, gamma, deltaN p63-alpha, -beta, and -gamma. The molecular weights of the p63 isoforms alpha=66 kD, beta=52 kD, and gamma=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. deltaN isoforms are antagonistic to p53; TA isoforms can transactivate p53 targets. The p63 deltaN isoforms repress TA isoforms; mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and deltaN isoforms. The Poly6190 antibody recognizes human p63 deltaN isoforms and has been shown to be useful for Western blotting.
Catalogue number: 619002
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 200 microl
Clone: Poly6190
Gene: 8626
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store frozen at -20 C.
Antigen: Modified peptide
Isotype: Rabbit Polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: p63, Isoforms TA p63-alpha, -beta, -gamma, deltaN p63-alpha, -beta, -gamma
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