Purified anti-NF-kappaB p65

Cat no: 653001

Supplier: BioLegend

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Description
Additional Information

NF-kB p65 is a member of REL-like domain containing protein family, which forms NF-kB complex with the other family members: NF-kappaB1 (p105/p50) or NF-kappaB2 (p100/p52). The NF-kB complex is inactivated and held in the cytoplasm by the NF-kB inhibitor IkB. In response to activation stimuli, IkB kinases (IKKs) phosphorylate IkB, resulting in degradation of IkB and liberation of NF-kB complex. The activated NF-kB complex translocates to the nucleus and binds to kB sites in the DNA of their target genes.

Catalogue number:	653001
Reactivities:	Human, Mouse, Rat
Hosts:	Mouse
Applications:	Western Blot
Size:	25 microg
Clone:	14G10A21
Gene:	4790
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-0.5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Partial human NF-kappaB p65 recombinant protein (451-551 aa)
Isotype:	Mouse IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Nuclear factor NF-kappa-B p65 subunit (NF-kB p65), Rel-A, transcription factor p65, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (NFKB3)