Home  >  Products  >  Neuro?lament H, 200kD, Bovine (NF-H)

Neuro?lament H, 200kD, Bovine (NF-H)

Cat no: N2160-15

Supplier: United States Biological
0 reviews | Write a Review Pencil
Neurofilaments can be defined as the intermediate or 10nm filaments found in specifically in neuronal cells. In the electron microscope neurofilaments appear as 10nm diameter fibres of indeterminate length which generally have fine wispy protrusions from their sides. They are found particularly abundantly in axons of large projection neurons. They probably function to provide structural support for neurons and their synapses and to support the large axon diameters required for rapid conduction of impulses down axons. They are composed a mixture of subunits which usually include the three neurofilament triplet proteins known as NFL, NFM and NFH. Neurofilaments may also include smaller amounts of peripherin, alpha internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable. Isoelectric Point: pI ~5 Applications: Suitable for use as a Protein standard in 1D and 2D SDS-gel-electrophoresis, immunoassays and as an antigen for immunization. Other applications have not been tested. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: N2160-15
Applications: ELISA
Size: 50ug
Form: Supplied as a liquid in 10mM sodium phosphate, pH 7.5, 2mM DDT, 6M urea, 1mM EDTA.
Purity: (same/more than) 98% (SDS-PAGE)
References: 1. Dahl, D., et al., Analyt. Biochem. 126: 165 ff, (1982). 2. Weber, K., et al., Cold Spring Harbor Symp. Quant. Biol. 48: 717 ff, (1983)

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave