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Myeloperoxidase (MPO, pANCA)

Myeloperoxidase (MPO, pANCA)

Cat no: M9760-06F

Supplier: United States Biological
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Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140kD. The glycoslated form of MPO has a molecular weight of 92kD and when undergoes a final glycoslyation, MPO forms subunits of 60kD and 12kD. In recent studies, MPO was shown to be involved in the initiation and progression of cardiovascular disease. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: M9760-06F
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human MPO at ~60-100kD. Species Crossreactivity: mouse and rat.

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