MBD2a (Methyl CpG Binding Domain Protein 2a, Demethylase, DMTase, DKFZp586O0821, MBD2, Methyl CpG Binding Domain Protein 2 Isoform 1, Methyl CpG Binding Protein MBD2, NY-CO-41)

Cat no: M2472-01A

Supplier: United States Biological

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The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414aa protein, whereas MBD2b lacks the 152aa N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	M2472-01A
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by affinity chromatography.
Additional info:	Recognizes rat MBD2a. Species Crossreactivity: human and mouse.

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MBD2a (Methyl CpG Binding Domain Protein 2a, Demethylase, DMTase, DKFZp586O0821, MBD2, Methyl CpG Binding Domain Protein 2 Isoform 1, Methyl CpG Binding Protein MBD2, NY-CO-41)

Cat no: M2472-01A

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