KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. KLF4 can act as both a repressor and activator of transcription. KLF4 regulates the expression of key transcription factors during embryonic development and is important in maintaining embryonic stem cells. It also contributes to the down-regulation of p53/TP53 transcription.
Suitable for use in Western Blot. Other applications not tested.
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.