Home  >  Products  >  Interleukin 8 (IL-8, 310C, AMCF1, b-ENAP, Beta Thromboglobulin-like Protein, CXCL8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP1, K60, LECT, LUCT, Lymphocyte-derived Neutrophil Activating Factor, LYNAP, MONAP, Monocyte Derived Neutrophil Activating
Interleukin 8 (IL-8, 310C, AMCF1, b-ENAP, Beta Thromboglobulin-like Protein, CXCL8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP1, K60, LECT, LUCT, Lymphocyte-derived Neutrophil Activating Factor, LYNAP, MONAP, Monocyte Derived Neutrophil Activating

Interleukin 8 (IL-8, 310C, AMCF1, b-ENAP, Beta Thromboglobulin-like Protein, CXCL8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP1, K60, LECT, LUCT, Lymphocyte-derived Neutrophil Activating Factor, LYNAP, MONAP, Monocyte Derived Neutrophil Activating

Cat no: I8430-03N

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Chemokines are a group of small approximately 8 to 14kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors (1). Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to inflammatory stimuli (e.g., interleukin-1 or tumor necrosis factor) and activates neutrophils inducing chemotaxis, exocytosis and the respiratory burst. In vivo, IL-8 elicits a massive neutrophil accumulation at the site of injection (2). It has recently been shown that IL-8, through its effects on the macrophage and endothelial cell, may be involved in the pathogenesis of atherosclerosis (3). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: I8430-03N
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Belperio JA, et al. J Leukoc Biol 68(1):1-8, 2000 2. Baggiolini M, et al. FEBS Lett. 307(1):97-101, 1992 3. Bruun JM, et al. J Clin Endocrinol Metab 86(3):1267-73 2001
Additional info: Recognizes human IL-8.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave