Home  >  Products  >  GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)
GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

Cat no: G8250-31

Supplier: United States Biological
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Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-b and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Immunohistochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8250-31
Reactivities: Human, Mouse, Rat, Rabbit
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human Ga15. Species Crossreactivity: mouse, rat and rabbit.

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