Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-3 encodes a ~30-35kD protein containing a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.