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Products GABA(A)R, Beta2/3
| Catalogue number: | 73-363, 75-383 |
| Reactivities: | Human, Mouse, Rat, Bovine, Chicken/Bird |
| Hosts: | Mouse |
| Applications: | Immunocytochemistry, Immunohistochemistry, Immunoprecipitation |
| Conjugates: | Unconjugated |
| Size: | 5 mL (TC supernatant), 100ul (pure) |
| Clone: | 62-3G1 |
| Accession: | P28472 |
| Antigen: | Fraction of bovine brain GABA-A receptor affinity purified against immobilized benzodiazepine Ro7-1986/1 (1988 de Blas et al J Neurosci PMID 2828565, 1988 Vitorica et al J Neurosci PMID 2828566). Target initially identified as a GABA-A receptor by: (1) rat brain immunocytochemistry staining pattern via light microscopy identical to that seen via ligand autoradiography with 3H-muscimol, (2) immunoprecipitation of 3H-muscimol-binding activity of the purified receptor complex and (3) recognition of ~57 kDa protein in immunoblots against crude rat brain membrane fractions. Binding epitope identified to be within amino acids 26-40 (QSVNDPGNMSFVKET, extracellular N-terminus, 1992 Ewert et al Brain Res, PMID 1377081) of human GABA-A-R-Beta3 (also known as Gamma-aminobutyric acid receptor subunit beta-3 |
| Format: | TC Supe, Pure |
| P type: | Monoclonal |
| Species: | Bovine |
| Isotype: | IgG1 |
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