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Fragilis (Interferon-induced Transmembrane Protein 3, Interferon-inducible Protein 1-8U, IFITM3)

Fragilis (Interferon-induced Transmembrane Protein 3, Interferon-inducible Protein 1-8U, IFITM3)

Cat no: F6072-60C

Supplier: United States Biological
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Fragilis (IFITM3) is a 133aa protein belonging to the CD225 family and contains an N-terminal signal sequence, three potential phosphorylation sites and a C-terminal leucine zipper. It plays a role in cell adhesion and cell differentiation. It behaves as a homing signal, enabling the cells localization. IFITM3 protein is approximately 90% identical to IFITM2. The guidance activities of IFITM1 and IFITM3 were mediated by their unique N-terminal domains. It is expressed on the surface of primordial germ cells Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F6072-60C
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Lewin, AR. et al. Eur. J. Biochem. 199:417-423 (1991). 2. Tanaka, SS. et al. Dev. Cell. 9:745-756 (2005).
Additional info: Recognizes mouse Fragilis. Species Crossreactivity: rat. Species sequence homology: bovine.

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