Home  >  Products  >  Flt1 (Fms-like Tyrosine Kinase 1, Vascular Endothelial Growth Factor Receptor 1, VEGF R1)
Flt1 (Fms-like Tyrosine Kinase 1, Vascular Endothelial Growth Factor Receptor 1, VEGF R1)

Flt1 (Fms-like Tyrosine Kinase 1, Vascular Endothelial Growth Factor Receptor 1, VEGF R1)

Cat no: F4599-03G

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Human Flt-1 is a type I transmembrane receptor for the angiogenic cytokine, VEGF. Alternate splicings of human VEGF R1 mRNA encode soluble, secreted isoforms that can function as inhibitors of VEGF. One, designated sFLT1-14 or sFLT1-e15a, encodes a 733aa, 95-135kD form that is produced by non-endothelial cells, notably by degenerative syncytiotrophoblasts within syncytial knots in the placenta. This form appears to be unique to primates and is produced in excess during preeclampsia of pregnancy. The peptide used as an immunogen is not present within either the full-length or alternate secreted forms of the protein. Applications: Suitable for use in Western Blot and Direct ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 2ug/ml using human serum (preeclampsia) Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F4599-03G
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human Flt1. In Direct ELISA and Western Blot there is no crossreactivity with recombinant mouse VEGF R1, recombinant human VEGFR1, VEGF R2, or recombinant human VEGF R3.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave