Home  >  Products  >  Fkbp1a (Peptidyl-prolyl Cis-trans Isomerase FKBP1A, PPIase FKBP1A, 12kD FK506-binding Protein, 12kD FKBP, FKBP-12, Calstabin-1, FK506-binding Protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, Fkbp1)
Fkbp1a (Peptidyl-prolyl Cis-trans Isomerase FKBP1A, PPIase FKBP1A, 12kD FK506-binding Protein, 12kD FKBP, FKBP-12, Calstabin-1, FK506-binding Protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, Fkbp1)

Fkbp1a (Peptidyl-prolyl Cis-trans Isomerase FKBP1A, PPIase FKBP1A, 12kD FK506-binding Protein, 12kD FKBP, FKBP-12, Calstabin-1, FK506-binding Protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, Fkbp1)

Cat no: F4150-11D

Supplier: United States Biological
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FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Immunoprecipitation: 2-10ug/ml Immunohistochemistry: 2-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F4150-11D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes mouse FKBP12 at ~12kD. Species Crossreactivity: Human and rat.

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