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Fas (CD95, APO-1) (FITC)

Fas (CD95, APO-1) (FITC)

Cat no: F0019-61K

Supplier: United States Biological
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Human CD95 (APO-1/FAS) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response. Functional Application: Antibody will not induce apoptosis of cells expressing CD95. Applications: Suitable for use in Flow Cytometry and ELISA. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0019-61K
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry
Size: 120Tests
Form: Supplied as a liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 5% glycerol, 0.2% BSA, 0.04% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1142-1148. 2. S. Nagata & P. Golstein (1995) Science 267: 1449-1456. 3. S. Nagata & T. Suda (1995) Immunol Today 16: 39-43. 4. D.H. Lynch, F. Ramsdell & M.R. Alderson (1995) Immunol Today 16: 569-574.
Additional info: Reacts with cell surface expressed CD95.

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