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Products COX-2 (mouse) Polyclonal Antiserum
| Catalogue number: | 160116 |
| Hosts: | Rabbit |
| Applications: | Immunohistochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | mouse COX-2 amino acids 584-598 (SHSRLDDINPTVLIK){1982,1306} |
| P type: | Antibodies|Cyclooxygenase |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions. COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep. |
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