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CD71 (Transferrin Receptor, TR, Tfr, TfnrR) (PE/CY5)

Cat no: C2426-15L

Supplier: United States Biological
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CD71 is a 95kD type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin.1-4 Applications:
Catalogue number: C2426-15L
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE/CY5.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD71 Section, Academic Press, New York, p. 320 2. Tetsa, U., E. Pelosi, and C. Peschle 1993. Crit. Rev. Oncog. 4:241. 3. Trowbridge, I.S., J.F. Collawn, and C.R. Hopkins. 1993. Annu. Rev. Cell Biol. 9:129. 4. Hentze, M.W., and L.C. Kuhn. 1996. Proc. Natl. Acad. Sci. USA 93:8175.
Additional info: Recognizes human CD71.

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