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Cat no: C2257-01F

Supplier: United States Biological
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Human CD6 is expressed on peripheral blood T cells, most thymocytes and a subset of B cells. CD6 is similar to CD5 and contains three cysteine-rich domains with structural homology to the macrophage scavenger receptor. CD6 is involved in T cell activation and its ligand was recently identified. Functional Application: Antibody is a useful reagent to study T cell activation through CD6. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2257-01F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Size: 120Tests
Form: Supplied as a liquid in PBS, pH 7.2, 5% glycerol, 0.2% BSA, 0.05% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein A affinity chromatography.
References: 1. C.M. Bott, et al, (1993) Int Immunol 5: 783-792. 2. M.A. Bowen, et al, (1995) J Exp Med 181: 2213-2220. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 3. 419-422. 4. G.S. Whitney, et al, (1995) J Biol Chem 270: 18187-18190.
Additional info: Recognizes CD6 molecules of approximately 130kD. Antibody is a useful reagent to study T cell activation through CD6.

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