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CD105 (Endoglin, gp160, TGF beta1,3 Receptor) (PE)

Cat no: C2446-51B

Supplier: United States Biological
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CD105, also known as endoglin, is a 95kD type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGFbeta, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications have not been tested. Recommended Dilution: Flow Cytometry: 5ul/10e6 cells Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Note: We do not recommended adding glycerol as a cryopreservative.
Catalogue number: C2446-51B
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD105 Section, Academic Press, New York, p. 384. 3. Lastres, P., T. Bellon, C. Cabanas, F. Martin-Perez, A. Acevedo, A. Gougos, M. Letarte, and C. Bernabeu. 1992. Eur. J. Immunol. 22:393. 4. Lopez-Casilias, F., S. Cheifetz, J. Doody, J.L. Andres, W.S. Lane, and J. Massague. 1991. Cell 67:785. 5. Fernandez-Ruiz, E., S. St-Jacques, T. Bellon, M. Letarte, and C. Bernabeu. 1993 Cytogonet. Cell Genet. 64:204. 6. 231. Bellon, T., A. Corbi, P. Lastres, C. Cales, M. Cebrian, S. Vera, S. Cheifetz, J. Massague, M. Letarte, and C. Bernabeu. 1993. Eur. J. Immunol. 23:2340. 7. Lastres, P., J. Martin-Perez, C. Langa, and C. Bernabeu. 1994. Biochem. J. 301:765. 8. Westenend, P.J., et al. 1994. J. Am. Soc. Neph. 5:822.
Additional info: Recognizes human CD105.

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