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Products Caspase 8 (CASP8, CASP-8, ALPS2B, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like Protease, FADD-like ICE, FLICE, FLJ17672, ICE-like Apoptotic Protease 5, MORT1-associated Ced-3 Homolog, MACH, MCH5, MGC78473)
| Catalogue number: | C2087-34F |
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | Immunocytochemistry, Immunoprecipitation, Western Blot |
| Size: | 50ug |
| Form: | Supplied as a liquid in PBS, 0.02% sodium azide, before the addition of glycerol to 40%. |
| P type: | Mab |
| Isotype: | IgG2b |
| Purity: | (same/more than) 95% SDS-PAGE |
| References: | 1. C. Scaffidi, et al.; J. Biol. Chem. 272, 26953 (1997) Abstract; Full Text Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8: M.R. Sprick, et al.; EMBO J. 21, 4520 (2002) M. Leverkus, et al.; Mol. Cell. Biol. 23, 777 (2003) Abstract; Full Text Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice: S.T. Eichhorst, et al.; Nature Med. 10, 602 (2004) Abstract. T.M. Ganten, et al.; Cell Death Differ. 11 Suppl 1, S86 (2004) Abstract |
| Additional info: | Recognizes the p18 subunit of human caspase-8. |
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